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Quinacrine dihydrochloride

Cat. No. M3183

All AbMole products are for research use only, cannot be used for human consumption.

Quinacrine dihydrochloride Structure
Synonym:

Mepacrine dihydrochloride; SN-390

Size Price Availability Quantity
25mg USD 30  USD30 In stock
50mg USD 45  USD45 In stock
100mg USD 50  USD50 In stock
200mg USD 80  USD80 In stock
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Quality Control & Documentation
Biological Activity

Quinacrine dihydrochloride is an inhibitor of cPLA2, MAO-A and MAO-B. Quinacrine dihydrochloride is a non-specific PLA2 (phospholipase A2) inhibitor. Quinacrine dihydrochloride acts as an AChR (acetylcholine receptor) antagonist. Quinacrine dihydrochloride suppresses glibenclamide-sensitive K+-currents (IC50 = 4.4 μM).

Chemical Information
Molecular Weight 472.88
Formula C23H30ClN3O.2HCl
CAS Number 69-05-6
Solubility (25°C) DMSO 30 mg/mL
Water 10 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Clemence Delaye, et al. Access and use of quinacrine (mepacrine) in the treatment of resistant giardiasis

[2] Romain Rotival, et al. Determination of quinacrine dihydrochloride dihydrate stability and characterization of its degradants

[3] Aida M Cancel, et al. A one-year neonatal mouse carcinogenesis study of quinacrine dihydrochloride

[4] M J Van Beek, et al. Antimalarials

[5] J Zipper, et al. Quinacrine revised

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Keywords: Quinacrine dihydrochloride, Mepacrine dihydrochloride; SN-390 supplier, Anti-infection, inhibitors, activators

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