Free shipping on all orders over $ 500

Pseudojervine

Cat. No. M40348
Pseudojervine Structure
Size Price Availability Quantity
Free Delivery on orders over USD 500 Bulk Inquiry?
Quality Control & Documentation
Biological Activity

Pseudojervine is a glycoalkaloid with a feeble inhibition activity against platelet aggregation.

Chemical Information
Molecular Weight 587.74
Formula C33H49NO8
CAS Number 36069-05-3
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Benedict Mathews Paul et al. Food Chem. Exploring the hypoglycaemic efficacy of bio-accessed antioxidative polyphenolics in thermally processed Cucumis dipsaceus fruits - An in vitro and in silico study

[2] Jianbo Chen et al. Biomed Chromatogr. Quantitative determination of six steroid alkaloids by sensitive hydrophilic interaction liquid chromatography electrospray ionization mass spectrometry and its application to pharmacokinetic study in rats

[3] Tuba Aydin et al. Chem Biodivers. Insecticidal metabolites from the rhizomes of Veratrum album against adults of Colorado potato beetle, Leptinotarsa decemlineata

[4] Jian Tang et al. Phytother Res. Antitumor and antiplatelet activity of alkaloids from veratrum dahuricum

[5] O KRAYER. J Pharmacol Exp Ther. Studies on veratrum alkaloids. XII. A quantitative comparison of the antiaccelerator cardiac action of veratramine, veratrosine, jervine and pseudo-jervine

Related Others Products
Lutonarin

Lutonarin is a antioxidant agent that can be isolated from green barley leaves. Lutonarin (Isoorientin 7-O-glucoside) is a natural product found in aerial part of Silene jeniseensis.
Ethyl glucoside

Ethyl glucoside is a kind of phenolic compound. Ethyl β-D-glucopyranoside can be isolated from ethanolic extract of Scabiosa stellata LS.
Methyl 2,4-dihydroxyphenylacetate

Methyl 2,4-dihydroxyphenylacetate is a natural product isolated from Nigella damascena seeds with selective phytotoxic effects.
Magnesium Lithospermate B

Magnesium Lithospermate B is a derivative of caffeic acid tetramer extracted from Salviae miltiorrhizae. Magnesium Lithospermate B is widely used for the research of cardiovascular diseases, and it can protect against glucose-induced intracellular oxidative damage. Magnesium Lithospermate B also suppresses neuroinflammation and attenuates neurodegeneration.
5-O-Methylvisamminol

5-O-Methylvisamminol, a (furo) chromone identified in the extract of T. glauca. 5-O-Methylvisamminol is useful in (chemical) phylogeny and is a possible excellent chemotaxonomic marker for Apiaceae.
  Catalog
Abmole Inhibitor Catalog




Keywords: Pseudojervine supplier, Others, inhibitors, activators

 
Get to Know Us
Customer Support
Resources
Contact Us

Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2023 AbMole BioScience. All Rights Reserved.