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Protein kinase inhibitors 1 hydrochloride

Cat. No. M14890

All AbMole products are for research use only, cannot be used for human consumption.

Protein kinase inhibitors 1 hydrochloride Structure

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Quality Control & Documentation
Biological Activity

Protein kinase inhibitors 1 hydrochloride is a potent HIPK2 inhibitor, with IC50s of 136 and 74 nM for HIPK1 and HIPK2, and a Kd of 9.5 nM for HIPK2.

Chemical Information
Molecular Weight 419.89
CAS Number 2321337-71-5
Solubility (25°C) Water 9.09 mg/mL
DMSO 8.33 mg/mL
Storage 2-8°C, dry, sealed
References

[1] Ahmed A Abdelgalil, et al. Erlotinib

[2] Martin Steins, et al. Erlotinib

[3] Zuyao Yang, et al. Comparison of gefitinib, erlotinib and afatinib in non-small cell lung cancer: A meta-analysis

[4] R E Martell, et al. Effects of protein kinase inhibitors 1(5-isoquinolinesulfonyl)-2-methylpiperazine dihydrochloride (H-7) and N-[2-guanidinoethyl]-5-isoquinolinesulfonamide hydrochloride (HA1004) on calcitriol-induced differentiation of HL-60 cells

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Keywords: Protein kinase inhibitors 1 hydrochloride supplier, inhibitors, activators

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