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Prostratin

Cat. No. M7163

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Prostratin Structure
Size Price Availability
1mg USD 260  USD260 3-4 Weeks
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Quality Control & Documentation
Biological Activity

Prostratin is a pKC activator, with a Ki of 12.5 nM. Prostratin is also an NF-κB activator.

Prostratin inhibits growth and induces differentiation of AML cell lines. Prostratin enhances cytarabine-induced differentiation of AML cells.

Prostratin inhibits tumorigenesis in KRAS mutant pancreatic cancer cells and reduces tumor growth in mouse pancreatic tumor models.

Chemical Information
Molecular Weight 390.47
Formula C22H30O6
CAS Number 60857-08-1
Solubility (25°C) DMSO 40 mg/mL
Storage 4°C, protect from light
References

[1] Zhang, et al. PLoS One. Carbon monoxide-releasing molecule-2 reduces intestinal epithelial tight-junction damage and mortality in septic rats.

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Keywords: Prostratin supplier, PKC, inhibitors, activators

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