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Promethazine has strong sedative and weak antipsychotic effects. Promethazine reduces motion sickness and has antiemetic and anticholinergic properties. The apparent ability of topical H1r/2r antagonists to target epidermal H1/2r is translated into increased efficacy in the treatment of inflammatory dermatoses, likely due to decreased inflammation and enhanced barrier function.
| Molecular Weight | 320.88 |
| Formula | C17H21ClN2S |
| CAS Number | 58-33-3 |
| Solubility (25°C) | DMSO |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related Histamine Receptor Products |
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| Betazole
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