All AbMole products are for research use only, cannot be used for human consumption.
Antiviral [herpes simplex virus (HSV) and human immunodeficiency virus (HIV)], antibacterial, superoxide radical-scavenging, and complement-modulating properties were assessed. In general, more pronounced activities were seen with epicatechin-containing dimers for anti-HSV, anti-HIV, and radical-scavenging effects, while the presence of ortho-trihydroxyl groups in the B-ring was important in compounds exhibiting anti-HSV and radical-scavenging effects and complement classical pathway inhibition.
 |
Source | Can J Physiol Pharmacol (2012). Figure 6. Procyanidin B4 |
| Method | AGE formation assay | |
| Cell Lines | ||
| Concentrations | 50 to 100 mg | |
| Incubation Time | ||
| Results | No single biomarker could efficiently and significantly predict antiglycation activity. |
| Cell Experiment | |
|---|---|
| Cell lines | RAW 264.7 cells |
| Preparation method | At 80-90% confluency, the medium was replaced with a colorless DMEM medium with antibiotics and without FBS, and then the cells were stimulated with LPS and coincubated with procyanidins and PUFAs with a final concentration for the following compounds: B1, B2, B3, and B4 (5 mg/mL or 8.64 μM), and DHA and EPA (30 μM). After 19 h of treatment, the supernatant was collected and stored at -20℃. |
| Concentrations | 8.64 μM |
| Incubation time | 19 h |
| Animal Experiment | |
|---|---|
| Animal models | male castrated pigs |
| Formulation | water |
| Dosages | 10 mg/kg |
| Administration | oral |
| Molecular Weight | 578.52 |
| Formula | C30H26O12 |
| CAS Number | 29106-51-2 |
| Solubility (25°C) | DMSO |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related Others Products |
|---|
| 4-O-Galloylalbiflorin
4-O-Galloylalbiflorin is a natural product that can be derived from the root of Paeonia lactiflora pall. |
| Licoricesaponin E2
Licoricesaponin E2 is a triterpene saponinthat can be found in Glycyrrhiza inflata. |
| Uralsaponin B
Uralsaponin B is a natural product. |
| Daturataturin A aglycone
Daturataturin A aglycone is a natural Steroids isolated from the herbs of Datura tatura. Daturataturin A aglycone can be used for research related to life sciences. |
| (4->2)-Abeo-16-hydroxycleroda-2,13-dien-15,16-olide-3-al
(4→2)-Abeo-16-hydroxycleroda-2,13-dien-15,16-olide-3-al is extracted from the unripe fruits of Polyalthia longifolia var. pendula. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.
