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Prezalumab

Cat. No. M24709

All AbMole products are for research use only, cannot be used for human consumption.

Prezalumab Structure
Synonym:

AMG 557

Price and Availability

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Quality Control & Documentation
Biological Activity

Prezalumab (AMG 557) is a humanized IgG2 monoclonal antibody targets ICOSL and BAFF. Prezalumab demonstrates beneficial activities on the arthritis of systemic lupus erythematosus. Prezalumab can be used for the research of sjogren's syndrome cutaneous lupus erythematosus, psoriasis and systemic lupus erythematosus (SLE).

Chemical Information
CAS Number 1523164-68-2
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Stacey R Dillon, et al. Arthritis Rheumatol. Non-Redundant Roles of T Cell Costimulation Pathways in Inflammatory Arthritis Revealed by Dual Blockade of ICOS and CD28 with Acazicolcept (ALPN-101)

[2] Elena Pontarini, et al. Clin Exp Rheumatol. Blocking T cell co-stimulation in primary Sjögren's syndrome: rationale, clinical efficacy and modulation of peripheral and salivary gland biomarkers

[3] Clio P Mavragani, et al. J Autoimmun. Sjögren's syndrome: Old and new therapeutic targets

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Keywords: Prezalumab, AMG 557 supplier, inhibitors, activators

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