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PRE-084 hydrochloride is a highly affinity selective σ1 agonist with an IC50 value of 44 nM in the sigma receptor detection.
| Molecular Weight | 353.88352 |
| Formula | C19H28ClNO3 |
| CAS Number | 75136-54-8 |
| Form | Solid |
| Solubility (25°C) | DMSO ≥ 20 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related Sigma Receptor Products |
|---|
| IPAG
IPAG is a potent sigma-1 receptor antagonist with a pKi of 4.3. |
| PB28 dihydrochloride
PB28 dihydrochloride, a cyclohexylpiperazine derivative, is a high affinity and selective sigma 2 (σ2) receptor agonist with a Ki of 0.68 nM. |
| (±)-PPCC hemioxalate
(±)-PPCC hemioxalate is a compound that has the ability to regulate the activity of the sigma-1 receptor. |
| (+)-Igmesine hydrochloride
(+)-Igmesine hydrochloride (JO1784) is an orally active and selective σ receptor ligand with neuroprotective and anti-amnesic activities. |
| ANAVEX 3-71
ANAVEX 3-71 is an orally active SIGMAR1 receptor agonist and M1-positive variant modulator for studies related to schizophrenia. |
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