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Polygodial is a tRPA1 channel activator (EC50 = 400 nM) that is selective against TRPV1, TRPV2, TRPV3, TRPV4 and TRPM8 channels. Acts as an analgesic via desensitization of sensory neurons. Also exhibits antifungal activity via inhibition of mitochondrial ATPase.
| Molecular Weight | 234.33 |
| Formula | C15H22O2 |
| CAS Number | 6754-20-7 |
| Solubility (25°C) | DMSO 23.43 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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