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Podocarpic acid

Cat. No. M22525

All AbMole products are for research use only, cannot be used for human consumption.

Podocarpic acid Structure
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Biological Activity

Podocarpic acid is a natural product, which acts as a novel TRPA1 activator. Podocarpic acid anhydride acts as a 1 nM agonist of LXR alpha and beta receptors. It shows over 8-10-fold better activator of LXR receptors compared to one of the natural ligands, 22-(R)-hydroxy cholesterol, in HEK-293 cells.

Chemical Information
Molecular Weight 274.35
Formula C17H22O3
CAS Number 5947-49-9
Solubility (25°C) DMSO 100 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Steven A Li, et al. Bioorg Med Chem. Valorisation of the diterpene podocarpic acid - Antibiotic and antibiotic enhancing activities of polyamine conjugates

[2] Md Shahinozzaman, et al. Z Naturforsch C J Biosci. A review on chemistry, source and therapeutic potential of lambertianic acid

[3] Angela La Bella, et al. Molecules. (+)-Podocarpic Acid as Chiral Template in the Synthesis of Aphidicolane, Stemodane and Stemarane Diterpenoids †

[4] Hany Nashaat Baraka. Planta Med. Microbial transformation of podocarpic acid and evaluation of transformation products for antioxidant activity

[5] C W BRANDT, et al. Nature. Podocarpic acid as a source of an oestrogenic hormone

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Keywords: Podocarpic acid supplier, TRP Channel, inhibitors, activators

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