Free shipping on all orders over $ 500

Podocarpic acid

Cat. No. M22525

All AbMole products are for research use only, cannot be used for human consumption.

Podocarpic acid Structure

Price and Availability

For this product's availability, delivery time and price, please email [email protected] directly or click the "Inquiry Now" button below.


Quality Control & Documentation
Biological Activity

Podocarpic acid is a natural product, which acts as a novel TRPA1 activator. Podocarpic acid anhydride acts as a 1 nM agonist of LXR alpha and beta receptors. It shows over 8-10-fold better activator of LXR receptors compared to one of the natural ligands, 22-(R)-hydroxy cholesterol, in HEK-293 cells.

Chemical Information
Molecular Weight 274.35
Formula C17H22O3
CAS Number 5947-49-9
Solubility (25°C) DMSO 100 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Steven A Li, et al. Bioorg Med Chem. Valorisation of the diterpene podocarpic acid - Antibiotic and antibiotic enhancing activities of polyamine conjugates

[2] Md Shahinozzaman, et al. Z Naturforsch C J Biosci. A review on chemistry, source and therapeutic potential of lambertianic acid

[3] Angela La Bella, et al. Molecules. (+)-Podocarpic Acid as Chiral Template in the Synthesis of Aphidicolane, Stemodane and Stemarane Diterpenoids †

[4] Hany Nashaat Baraka. Planta Med. Microbial transformation of podocarpic acid and evaluation of transformation products for antioxidant activity

[5] C W BRANDT, et al. Nature. Podocarpic acid as a source of an oestrogenic hormone

Related TRP Channel Products
Moringin

Moringin is a potent and selective TRPA1 ion channel natural agonist with an EC50 of 3.14 μM. Moringin does not activate or activates very weakly the vanilloids somatosensory channels TRPV1, TRPV2, TRPV3 and TRPV4, and the melastatin cooling receptor TRPM8.

(S)-ABT-102

(S)-ABT-102 is a potent TRPV1 antagonist, with an IC50 of 123 nM. (S)-ABT-102 can block the activation of TRPV1 by capsaicin.

Oleoyl Serotonin

Oleoyl Serotonin is a TRPV1 antagonist with IC50 value of 2.57 μM for human TRPV1.

ABT-102

ABT-102 (CHEMBL398338) is a potent and highly selective transient receptor potential vanilloid 1 (TRPV1) receptor antagonist.

MK-2295

MK-2295 (TRPV1 antagonist 5) is a potent TRPV1 antagonist. MK-2295 can be used for the research of chronic pain.

  Catalog
Abmole Inhibitor Catalog




Keywords: Podocarpic acid supplier, TRP Channel, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.