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(+)-(3R,8S)-Falcarindiol

Cat. No. M11180

All AbMole products are for research use only, cannot be used for human consumption.

(+)-(3R,8S)-Falcarindiol Structure
Synonym:

(3R,8S)-Falcarindiol; 3(R),8(S),9(Z)-Falcarindiol

Size Price Availability Quantity
1mg USD 55  USD55 In stock
5mg USD 155  USD155 In stock
10mg USD 255  USD255 In stock
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Quality Control & Documentation
Biological Activity

(+)-(3R, 8S)-Falcarindiol is polyacetylene obtained from carrots, has an antimycobacterial effect, the lowest inhibitory concentration of Mycobacterium tuberculosis H37Ra MIC and IC50 The values are 24 μM and 6 μM, respectively. Has anti-tumor and anti-inflammatory effects.

Chemical Information
Molecular Weight 260.37
Formula C17H24O2
CAS Number 225110-25-8
Form Liquid
Solubility (25°C) DMSO ≥ 60 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Wan-Li Tan, et al. ChemMedChem. Synthesis, Anticancer Activity, Structure-Activity Relationship and Mechanistic Investigations of Falcarindiol Analogues

[2] Morten Kobaek-Larsen, et al. BMC Res Notes. Effect of the dietary polyacetylenes falcarinol and falcarindiol on the gut microbiota composition in a rat model of colorectal cancer

[3] Taryn O'Neill, et al. J Ethnopharmacol. The Canadian medicinal plant Heracleum maximum contains antimycobacterial diynes and furanocoumarins

[4] Ludger Schmiech, et al. J Agric Food Chem. Structure determination of bisacetylenic oxylipins in carrots (Daucus carota L.) and enantioselective synthesis of falcarindiol

[5] G Zheng, et al. J Nat Prod. Stereoselective total synthesis of (3R,8S)-falcarindiol, a common polyacetylenic compound from umbellifers

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Keywords: (+)-(3R,8S)-Falcarindiol, (3R,8S)-Falcarindiol; 3(R),8(S),9(Z)-Falcarindiol supplier, Antibiotic, inhibitors, activators

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