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PLGA lactide:glycolide (50:50)

Cat. No. M15096

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PLGA lactide:glycolide (50:50) Structure
Synonym:

Poly(DL-lactide-co-glycolide)

Size Price Availability Quantity
5g USD 300  USD300 In stock
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Quality Control & Documentation
  • Purity: mol wt 12000-90000
  • COA
  • MSDS
Biological Activity

Poly(D,L-lactide-co-glycolide) is a synthetic amino acid that has been used to deliver macromolecular therapeutics. The transition temperature (Tg) is 45 ~ 55℃ when the molecular weight is above 30,000. When the molecular weight is below 30,000, the transition temperature (Tg) decreases gradually. It is soluble in most organic solvents such as methylene chloride, tetrahydrofuran, ethyl acetate, acetone, chloroform, and hexafluoroispropanol.

Chemical Information
Formula (C3H4O2)x(C2H2O2)y
CAS Number 26780-50-7
Solubility (25°C) Soluble in methylene chloride
tetrahydrofuran
ethyl acetate
acetone
chloroform
Storage -20°C, sealed
References

[1] Beibei Lin, et al. J Biomed Nanotechnol. Photodynamic Treatment of Colorectal Cancer Using Chlorin e6-Loaded Poly(lactide-co-glycolide)- Based Nanoparticles

[2] Anurag Dobhal, et al. J Mater Sci Mater Med. Influence of lactide vs glycolide composition of poly (lactic-co-glycolic acid) polymers on encapsulation of hydrophobic molecules: molecular dynamics and formulation studies

[3] Supharat Inphonlek, et al. Carbohydr Polym. Chitosan/carboxymethylcellulose-stabilized poly(lactide-co-glycolide) particles as bio-based drug delivery carriers

[4] Sarah Skidmore, et al. J Control Release. Complex sameness: Separation of mixed poly(lactide-co-glycolide)s based on the lactide:glycolide ratio

[5] Vinay Saini, et al. Vaccine. Poly(d,l)-lactide-co-glycolide (PLGA) microspheres as immunoadjuvant for Brugia malayi antigens

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Keywords: PLGA lactide:glycolide (50:50), Poly(DL-lactide-co-glycolide) supplier, inhibitors, activators

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