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Pizuglanstat (TAS-205)

Cat. No. M20834

All AbMole products are for research use only, cannot be used for human consumption.

Pizuglanstat (TAS-205) Structure

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Quality Control & Documentation
Biological Activity

Pizuglanstat (TAS-205) is a highly selective hematopoietic prostaglandin D synthase (HPGDS) inhibitor with an IC50 of 55.8 nM.

Chemical Information
Molecular Weight 508.61
Formula C₂₇H₃₆N₆O₄
CAS Number 1244967-98-3
Solubility (25°C) DMSO 100 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Nermina Ferizovic, et al. PLoS One. Prognostic indicators of disease progression in Duchenne muscular dystrophy: A literature review and evidence synthesis

[2] Yuki Murakami, et al. RSC Med Chem. Structure-activity relationship study of PROTACs against hematopoietic prostaglandin D2 synthase

[3] Hiroki Aoyagi, et al. Eur J Pharmacol. Potential synergistic effects of novel hematopoietic prostaglandin D synthase inhibitor TAS-205 and different types of anti-allergic medicine on nasal obstruction in a Guinea pig model of experimental allergic rhinitis

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Keywords: Pizuglanstat (TAS-205) supplier, inhibitors, activators

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