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Pipecolic acid

Cat. No. M15074

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Pipecolic acid Structure
Synonym:

piperidine-2-carboxylic acid

Size Price Availability Quantity
500mg USD 40  USD40 In stock
1g USD 60  USD60 In stock
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Quality Control & Documentation
Biological Activity

Pipecolic acid, a lysine metabolite, is an important immunomodulator in plants and humans, and an important precursor for many useful microbial secondary metabolites. Pipecolic acid slows ferroptosis in diabetic retinopathy by inhibiting the YAP-GPX4 signaling pathway. In addition, Pipecolic acid can be used as a diagnostic marker for pyridoxine-dependent epilepsy.

Chemical Information
Molecular Weight 129.16
Formula C6H11NO2
CAS Number 535-75-1
Solubility (25°C) Water 40 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Lennart Mohnike, et al. Plant Cell. The glycosyltransferase UGT76B1 modulates N-hydroxy-pipecolic acid homeostasis and plant immunity

[2] Keshun Yu, et al. Bio Protoc. Pipecolic Acid Quantification Using Gas Chromatography-coupled Mass Spectrometry

[3] Yeong-Hoon Han, et al. Enzyme Microb Technol. Enhancement of pipecolic acid production by the expression of multiple lysine cyclodeaminase in the Escherichia coli whole-cell system

[4] Asako Shigemura, et al. J Poult Sci. Intracerebroventricular Injection of L-Pipecolic Acid Exerts Hypnotic Effects Without Activating NMDA Receptors in Neonatal Chicks under Social Isolation-induced Stress

[5] Min He. J Ind Microbiol Biotechnol. Pipecolic acid in microbes: biosynthetic routes and enzymes

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Keywords: Pipecolic acid, piperidine-2-carboxylic acid supplier, Metabolite/Endogenous Metabolite, inhibitors, activators

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