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PIP-199 is a selective inhibitor of RMI (RecQ-mediated genome instability protein) core complex/MM2 interaction, with an IC50 of 36 μM. PIP-199 can be used for the research of sensitizing resistant tumors to DNA crosslinking chemotherapeutics.
| Molecular Weight | 456.54 |
| Formula | C27H28N4O3 |
| CAS Number | 622795-76-0 |
| Form | Solid |
| Solubility (25°C) | DMSO 41.67 mg/mL (ultrasonic and warming and heat to 60°C) |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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