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Phosphoribosyl pyrophosphate pentasodium

Cat. No. M21129
Phosphoribosyl pyrophosphate pentasodium Structure

PRPP pentasodium

Size Price Availability Quantity
5mg USD 200  USD250 In stock
10mg USD 280  USD350 In stock
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Quality Control
  • Current batch:
  • Purity >80%
  • COA
  • MSDS
Biological Activity

Phosphoribosyl pyrophosphate (PRPP) pentasodium is an important metabolite required for the biosynthesis of purine and pyrimidine nucleotides, the amino acids histidine and tryptophan, and the cofactors NAD and NADP.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

Chemical Information
Molecular Weight 499.98
Formula C5H14NaO14P3
CAS Number 108321-05-7
Purity >80%
Solubility Water ≥ 40 mg/mL
Storage -20°C , dry , sealed
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Keywords: Phosphoribosyl pyrophosphate pentasodium, PRPP pentasodium supplier, Endogenous Metabolite, inhibitors

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