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PF-06648671 is a novel, brain-penetrable, and orally active γ-secretase modulator (GSM). PF-06648671 reduces Aβ42 and Aβ40, with concomitant increases in Aβ37 and Aβ38 in vitro. PF-06648671 is used for the study of Alzheimer’s disease.
| Molecular Weight | 538.92 |
| Formula | C25H23ClF4N4O3 |
| CAS Number | 1587727-31-8 |
| Form | Solid |
| Storage | Powder -20°C |
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