Certificate of Analysis

 

Product Name: PF-06648671 
Catalog Number: M28634
CAS Number: 1587727-31-8

Physical and Chemical Properties
Formula: C25H23ClF4N4O3
Molecular Weight: 538.92
Form: Solid
Storage: Powder -20°C
Chemical Structure: PF-06648671  Structure
Analytical Data
QC Standard: ≥99.0%
H-NMR: Consistent with structure
Product Information
Description: PF-06648671 is a novel, brain-penetrable, and orally active γ-secretase modulator (GSM). PF-06648671 reduces Aβ42 and Aβ40, with concomitant increases in Aβ37 and Aβ38 in vitro. PF-06648671 is used for the study of Alzheimer’s disease.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.