All AbMole products are for research use only, cannot be used for human consumption.
PF-05231023 is an FGF21-receptor agonist, it is also a potential treatment for T2DM. PF-05231023 suppresses oxidative-stress-induced inflammation in photoreceptors. PF-05231023 decreases the variability of retinal NRF2 levels and displays a trend (non-significant) towards increased NRF2 levels in Akita mice. PF-05231023 (10 mg/kg; i.p.) reduces retinal inflammation in diabetic mice.
J Adv Res. 2024 Apr 9;S2090-1232(24)00134-6.
FGF21 ameliorates septic liver injury by restraining proinflammatory macrophages activation through the autophagy/HIF-1a axis
PF-05231023 purchased from AbMole
Transl Res. 2024 Sep;271:93-104.
Spleen derived monocytes regulate pulmonary vascular permeability in Hepatopulmonary syndrome through the OSM-FGF/FGFR1 signaling
PF-05231023 purchased from AbMole
Front Vet Sci. 2024 Jul 31;11:1429639.
PF-05231023 reduces lipid deposition in apolipoprotein E-deficient mice by inhibiting the expression of lipid synthesis genes
PF-05231023 purchased from AbMole
| Molecular Weight | 528.55 |
| Formula | C26H32N4O8 |
| CAS Number | 1037589-69-7 |
| Solubility (25°C) | DMSO 100 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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Products are for research use only. Not for human use. We do not sell to patients.
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