About 13 results found for searched term "FGFR" (0.066 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M8936 | FGFR4-IN-1 | FGFR |
| FGFR4-IN-1 is a potent and selective FGFR4 inhibitor with IC50 of 0.7 nM. | ||
| M10520 | FGFR1/DDR2 inhibitor 1 | Others |
| ABM-497585 | ||
| FGFR1/DDR2 inhibitor 1 is an orally active inhibitor of fibroblast growth factor receptor 1 (FGFR1) and discoindin domain receptor 2 (DDR2), with IC50 values of 31.1 nM and 3.2 nM, respectively. | ||
| M25005 | Recifercept | Fusion Proteins |
| TA-46 sFGFR3 | ||
| Recifercept (TA-46) is a soluble, recombinant fibroblast growth factor receptor 3 (FGFR3) molecule. Recifercept can be used as a decoy/ligand trap to decrease the amount of fibroblast growth factors that can bind to mutant FGFR3 receptors. Recifercept can be used for the research of achondroplasia. | ||
| M28061 | FIIN-1 | FGFR |
| FGFR irreversible inhibitor-1 | ||
| FIIN-1 is a potent, irreversible, selective FGFR inhibitor. FIIN-1 binds to FGFR1/2/3/4 and Flt1/4 with Kds of 2.8/6.9/5.4/120 nM and 32/120 nM respectively. The biochemical IC50s of FIIN-1 are 9.2, 6.2, 11.9, and 189 nM against FGFR1/2/3/4, respectively. | ||
| M43502 | FGFR1 inhibitor 7 | FGFR |
| FGFR1 inhibitor 7 is an inhibitor of FGFR1 Tyrosine Kinase with IC50 value of 0.33 nM. | ||
| M43503 | FGFR4-IN-16 | FGFR |
| FGFR4-IN-16 (CY-15-2) is a covalent inhibitor of FGFR-4 for cancer research. | ||
| M43504 | FGFR1 inhibitor-9 | FGFR |
| FGFR1 inhibitor-9 is an FGFR1 inhibitor (IC50s: 0.85 nM). | ||
| M43506 | FGFR1 inhibitor-8 | FGFR |
| FGFR1 inhibitor-8 is a FGFR1 inhibitor (IC50s: 0.5 nM). | ||
| M43507 | FGFR1 inhibitor-10 | FGFR |
| FGFR1 inhibitor-10 is an FGFR1 inhibitor (IC50: 28 nM). | ||
| M43508 | FGFR4-IN-14 | FGFR |
| FGFR4-IN-14 is a FGFR4 inhibitor (IC50: 2.4 nM. | ||
| M43552 | FGFR1/VEGFR2-IN-1 | VEGFR/PDGFR |
| FGFR1/VEGFR2-IN-1 is an FGFR1/VEGFR2 inhibitor. | ||
| M58708 | Recombinant Human FGFR2 Protein (HEK293, C-His) | Cytokines and Growth Factors |
| Fibroblast growth factor receptor 2; CD332 | ||
| FGFR2, also known as CD332, acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation, migration and apoptosis, and in the regulation of embryonic development. FGFR2 plays an essential role in the regulation of osteoblast differentiation, proliferation and apoptosis, and is required for normal skeleton development. It also promotes cell proliferation in keratinocytes and imature osteoblasts, but promotes apoptosis in differentiated osteoblasts. | ||
| M58709 | Recombinant Human FGFR1 Protein (HEK293, C-His) | Cytokines and Growth Factors |
| CD331; Fibroblast growth factor receptor 1 | ||
| FGFR1, also known as CD331, is a full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. | ||
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