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cGMP-dependent protein kinase (PKG I and PKG II) activator. Potent membrane permeant activator of both isozymes I α and I β of cGMP-dependent protein kinase. Common stimulators such as 8-Br-cGMP or 8-pCPT-cGMP mainly activate kinase subtype Iα.
| Molecular Weight | 467.3 |
| Formula | C18H15N5O7PNa |
| CAS Number | 78080-27-0 |
| Solubility (25°C) | Water: ~10 mmol |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Eleonora Vighi, et al. New cGMP analogues restrain proliferation and migration of melanoma cells
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