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PD-1/PD-L1-IN-20 (Example 21) is a small-molecule inhibitor of the PD-1/PD-L1 protein-protein interaction. PD-1/PD-L1-IN-20 blocks PD-1/PD-L1 with the IC50 of 5.29 nM. PD-1/PD-L1-IN-20 can be used for the research of cancers, infectious diseases and autoimmune diseases.
| Molecular Weight | 577.9 |
| Formula | C30H26BrClN2O3 |
| CAS Number | 2159138-01-7 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
[2] Chinmoy Ghosh, et al. J Cancer. A snapshot of the PD-1/PD-L1 pathway
[3] Yanyan Han, et al. Am J Cancer Res. PD-1/PD-L1 pathway: current researches in cancer
[4] Nyanbol Kuol, et al. Immunotherapy. PD-1/PD-L1 in disease
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