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Palmitoleic acid (Liquid)

Cat. No. M10078
Palmitoleic acid (Liquid) Structure
Size Price Availability Quantity
50mg USD 80  USD80 In stock
100mg USD 95  USD95 In stock
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Quality Control & Documentation
Biological Activity

Palmitoleic acid is found to be associated with isovaleric acidemia, which is an inborn error of metabolism.

Chemical Information
Molecular Weight 254.41
Formula C16H30O2
CAS Number 373-49-9
Solubility (25°C) DMSO ≥ 100 mM
Storage -20°C, dry, sealed
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Camila O de Souza, et al. J Cell Physiol. Palmitoleic Acid Improves Metabolic Functions in Fatty Liver by PPARα-Dependent AMPK Activation

[2] Y Yamori, et al. J Hypertens Suppl. Dietary prevention of stroke and its mechanisms in stroke-prone spontaneously hypertensive rats--preventive effect of dietary fibre and palmitoleic acid

[3] A Ogunleye, et al. J Nutr Sci Vitaminol (Tokyo). Fatty acid composition of breast milk from Nigerian and Japanese women

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