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Palmitic acid ethyl ester

Cat. No. M18238
Palmitic acid ethyl ester Structure
Size Price Availability Quantity
100mg USD 30  USD30 In stock
500mg USD 50  USD50 In stock
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Biological Activity

Palmitic acid ethyl ester

Chemical Information
Molecular Weight 284.48
Formula C18H36O2
CAS Number 628-97-7
Form Melting point 24-26 °C
Solubility (25°C) DMSO 90 mg/mL
Storage Pure form -20°C
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Qing Yin, et al. Polymers (Basel). Fabrication and Performance of Composite Microencapsulated Phase Change Materials with Palmitic Acid Ethyl Ester as Core

[2] Christie M Ballantyne, et al. Cardiol Ther. Icosapent Ethyl Effects on Fatty Acid Profiles in Statin-Treated Patients With High Triglycerides: The Randomized, Placebo-controlled ANCHOR Study

[3] David Oppolzer, et al. Biomed Chromatogr. Determination of ethyl glucuronide and fatty acid ethyl esters in hair samples

[4] S D Zuijdgeest-Van Leeuwen, et al. Clin Nutr. Eicosapentaenoic acid ethyl ester supplementation in cachectic cancer patients and healthy subjects: effects on lipolysis and lipid oxidation

[5] L Dan, et al. Alcohol Clin Exp Res. Ethyl palmitate and ethyl oleate are the predominant fatty acid ethyl esters in the blood after ethanol ingestion and their synthesis is differentially influenced by the extracellular concentrations of their corresponding fatty acids

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