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Oxolamine (SKF-9976, AF-438) citrate, a cough suppressant, is an inhibitor of CYP2B1/2. Oxolamine citrate also exhibits anti-inflammatory effect.
| Molecular Weight | 437.44 |
| Formula | C20H27N3O8 |
| CAS Number | 1949-20-8 |
| Solubility (25°C) | DMSO 87 mg/mL Water 43 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] L CARRATU. Gazz Med Ital. [Oxolamine citrate in geriatric practice]
[4] J McEwen, et al. Med J Aust. Hallucinations in children caused by oxolamine citrate
| Related Cytochrome P450 (e.g. CYP17) Products |
|---|
| (S)-Mephenytoin
(S)-Mephenytoin is a substrate of the cytochrome P450 (CYP) isoform CYP2C19. (S)-Mephenytoin can be used for the analysis of cytochrome P450 metabolism. |
| Cytochrome P450 reductase
Cytochrome P450 reductase is a NADPH-cytochrome reductase. |
| 20-SOLA
20-SOLA is a water-soluble 20-HETE antagonist. |
| TS-011
TS-011 is a selective inhibitor of 20-hydroxyeicosatetraenoic acid (20-HETE) synthesis. |
| Dibromo-dodecenyl-methylsulfimide
Dibromo-dodecenyl-methylsulfimide is a selective inhibitor of 20-HETE synthesis and attenuates the vasodilatory response to sodium nitroprusside (SNP). |
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