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Dehydro Nifedipine is the main metabolite of nifedipine in human plasma. Dehydro Nifedipine inhibits glucose uptake in PC-12 cells with an IC50 value of 130 μM. Nifedipine is an antianginal and antihypertensive agent. Oxidized nifedipine has been used for apoptotic signaling studies in dopaminergic neurons.
| Molecular Weight | 344.32 |
| Formula | C17H16N2O6 |
| CAS Number | 67035-22-7 |
| Solubility (25°C) | DMSO 20 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related Metabolite/Endogenous Metabolite Products |
|---|
| N-Desmethyl Imatinib
N-Desmethyl Imatinib |
| Desthiazolylmethyloxycarbonyl Ritonavir
Desthiazolylmethyloxycarbonyl Ritonavir is a metabolite of Ritonavir, which is a HIV protease inhibitor. |
| 4-Hydroxy phenyl carvedilol
4-Hydroxyphenyl Carvedilol is a metabolite of Carvedilol, which is a nonselective beta blocker/alpha-1 blocker. |
| Omeprazole sulfone
Omeprazole sulfone is a metabolite of Omeprazole, which is a proton pump inhibitor. |
| Duloxetine Phenolic Impurity
Para-Naphthol Duloxetine is a metabolite of Duloxetine, which is a serotonin-norepinephrine reuptake inhibitor (SNRI). |
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