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Oxiconazole

Cat. No. M30415

All AbMole products are for research use only, cannot be used for human consumption.

Oxiconazole Structure
Synonym:

Ro 13-8996 free base

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Quality Control & Documentation
Biological Activity

Oxiconazole (Ro 13-8996) is a broad spectrum anti-fungal agent which can inhibit the growth of Candida, Aspergillus and Trichophyton. Oxiconazole is also a highly efficacious activator of CYP3A4 transactivation, which could be antagonized by Rifampicin in a competitive manner. Oxiconazole exhibits inhibitory effect against colorectal cancer (CRC) via peroxiredoxin-2 (PRDX2)-mediated autophagy arrest.

Chemical Information
Molecular Weight 429.13
Formula C18H13Cl4N3O
CAS Number 64211-45-6
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Grace Kaul, et al. Microbiol Spectr. Oxiconazole Potentiates Gentamicin against Gentamicin-Resistant Staphylococcus aureus In Vitro and In Vivo

[2] Jinyu Shi, et al. Int J Biol Sci. Repurposing Oxiconazole against Colorectal Cancer via PRDX2-mediated Autophagy Arrest

[3] No authors listed. Oxiconazole

[4] Alper Arslan, et al. Saudi Pharm J. Evaluation of a novel oxiconazole nitrate formulation: The thermosensitive gel

[5] B V Jegasothy, et al. Clin Ther. Oxiconazole nitrate: pharmacology, efficacy, and safety of a new imidazole antifungal agent

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Keywords: Oxiconazole, Ro 13-8996 free base supplier, Antifungal, inhibitors, activators

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