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Oteseconazole

Cat. No. M10444

All AbMole products are for research use only, cannot be used for human consumption.

Oteseconazole Structure
Synonym:

VT-1161

Size Price Availability Quantity
1mg USD 120  USD120 In stock
5mg USD 240  USD240 In stock
10mg USD 360  USD360 In stock
50mg USD 960  USD960 In stock
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Quality Control & Documentation
Biological Activity

Oteseconazole (VT-1161) is an antifungal compound with oral activity that is highly selective for CYP51. It can effectively bind to and inhibit CYP51 of N. albicans (Kd <39 nM), but shows no obvious effect on human CYP51.

Chemical Information
Molecular Weight 527.39
Formula C23H16F7N5O2
CAS Number 1340593-59-0
Solubility (25°C) DMSO ≥ 100 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] E P Garvey, et al. Antimicrob Agents Chemother. VT-1161 dosed once daily or once weekly exhibits potent efficacy in treatment of dermatophytosis in a guinea pig model

[2] A G S Warrilow, et al. Antimicrob Agents Chemother. The clinical candidate VT-1161 is a highly potent inhibitor of Candida albicans CYP51 but fails to bind the human enzyme

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Keywords: Oteseconazole, VT-1161 supplier, Anti-infection, inhibitors, activators

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