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Orphenadrine Hydrochloride

Cat. No. M20518

All AbMole products are for research use only, cannot be used for human consumption.

Orphenadrine Hydrochloride Structure

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Quality Control & Documentation
Biological Activity

A muscarinic receptor antagonist, specifically an H1 histamine receptor antagonist. This compound is a muscle relaxant. Orphenadrine has also been reported to inhibit the noradrenergic transporter and to block the NMDA receptor ion channel.

Chemical Information
Molecular Weight 305.84
Formula C18H24ClNO
CAS Number 341-69-5
Solubility (25°C) DMSO 61 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Lorena Abril, et al. J Emerg Med. The Relative Efficacy of Seven Skeletal Muscle Relaxants. An Analysis of Data From Randomized Studies

[2] No authors listed. Orphenadrine

[3] Benjamin W Friedman, et al. Ann Emerg Med. A Randomized, Double-Blind, Placebo-Controlled Trial of Naproxen With or Without Orphenadrine or Methocarbamol for Acute Low Back Pain

[4] No authors listed. J Am Med Assoc. ORPHENADRINE hydrochloride

[5] F Schifano, et al. South Med J. Orphenadrine abuse

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