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Orm-3819 is a potent muscular compound that binds to cardiac troponin C (cTnC) and sensitizes the heart to Ca2+. Orm-3819 is also a selective and potent inhibitor of PDE III. Orm-3819 exhibits positive inotropic effects through Ca2+ sensitization and selective inhibition of PDE III. ORM-3819 is an effective myocardial block model in animals.
| Molecular Weight | 397.38 |
| Formula | C19H19N5O5 |
| CAS Number | 360794-85-0 |
| Solubility (25°C) | DMSO: 30 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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