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Org 20599 is a positive allosteric modulator and at higher concentrations direct agonist of GABAA receptors (EC50 = 1.1 μM). Also displays positive modulation of glycine receptors (EC50 = 22.9 μM). Anesthetic steroid; induces hypnosis and loss of righting reflexes in mice.
| Molecular Weight | 438.04 |
| Formula | C25H40ClNO3 |
| CAS Number | 156685-94-8 |
| Solubility (25°C) | 1eq. HCl 43.8 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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