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ONO-7300243

Cat. No. M20620

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ONO-7300243 Structure
Synonym:

ONO 7300243, ONO7300243

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Quality Control & Documentation
Biological Activity

ONO-7300243 is a novel, potent LPA1(Lysophosphatidic Acid Receptor) antagonist with an IC50 of 160 nM.

Chemical Information
Molecular Weight 461.55
Formula C28H31NO5
CAS Number 638132-34-0
Solubility (25°C) DMSO 92 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Satoshi Takagi, et al. Oncogene. Platelet-derived lysophosphatidic acid mediated LPAR1 activation as a therapeutic target for osteosarcoma metastasis

[2] Masahiko Terakado, et al. ACS Med Chem Lett. Discovery of a Slow Tight Binding LPA1 Antagonist (ONO-0300302) for the Treatment of Benign Prostatic Hyperplasia

[3] Masahiko Terakado, et al. ACS Med Chem Lett. Discovery of ONO-7300243 from a Novel Class of Lysophosphatidic Acid Receptor 1 Antagonists: From Hit to Lead

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  Catalog
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Keywords: ONO-7300243, ONO 7300243, ONO7300243 supplier, inhibitors, activators

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