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Ompenaclid (RGX-202-01) is an orally active inhibitor of SLC6A8 transport protein. Ompenaclid (RGX-202-01) strongly inhibits creatine import in vitro and in vivo, decreases intracellular phosphocreatine and ATP levels, and induces apoptosis. Ompenaclid (RGX-202-01) has been used in oncology and Duchenne muscular dystrophy studies.
| Molecular Weight | 131.13 |
| Formula | C4H9N3O2 |
| CAS Number | 353-09-3 |
| Solubility (25°C) | Water ≥ 40 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related Metabolite/Endogenous Metabolite Products |
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Gentisuric Acid is a metabolite of Aspirin, it is a substrate of α-amidating monooxygenase (PAM). Gentisuric acid prevents DNA-damage by Mitomycin C. |
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| Adenosine 2',3'-cyclic phosphate sodium
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| 6α-Hydroxy Paclitaxel
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| Casein (from bovine milk)
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