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Ompenaclid

Cat. No. M21357

All AbMole products are for research use only, cannot be used for human consumption.

Ompenaclid Structure
Synonym:

RGX-202-01; 3-Guanidinopropionic acid

Size Price Availability Quantity
5mg USD 20  USD20 In stock
50mg USD 30  USD30 In stock
100mg USD 40  USD40 In stock
500mg USD 60  USD60 In stock
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Quality Control & Documentation
Biological Activity

Ompenaclid (RGX-202-01) is an orally active inhibitor of SLC6A8 transport protein. Ompenaclid (RGX-202-01) strongly inhibits creatine import in vitro and in vivo, decreases intracellular phosphocreatine and ATP levels, and induces apoptosis. Ompenaclid (RGX-202-01) has been used in oncology and Duchenne muscular dystrophy studies.

Chemical Information
Molecular Weight 131.13
Formula C4H9N3O2
CAS Number 353-09-3
Solubility (25°C) Water ≥ 40 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] L David Wise, et al. Birth Defects Res B Dev Reprod Toxicol. Juvenile toxicity assessment of open-acid lovastatin in rats

[2] M Partinen, et al. Am J Cardiol. Comparison of effects on sleep of lovastatin and pravastatin in hypercholesterolemia

[3] H Y Pan, et al. J Clin Pharmacol. Comparative pharmacokinetics and pharmacodynamics of pravastatin and lovastatin

[4] A W Alberts. Cardiology. Lovastatin and simvastatin--inhibitors of HMG CoA reductase and cholesterol biosynthesis

[5] G Mantell. Therapie. [Extended worldwide experience. HMG-CoA reductase inhibitors: lovastatin and simvastatin]

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Keywords: Ompenaclid, RGX-202-01; 3-Guanidinopropionic acid supplier, Metabolite/Endogenous Metabolite, inhibitors, activators

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