All AbMole products are for research use only, cannot be used for human consumption.
Obtustatin is a potent integrin α1β1 inhibitor with IC50 of 0.8 nM for α1β1 binding to type IV collagen. Obtustatin inhibits FGF2-stimulated angiogenesis in the chicken chorioallantoic model. Obtustatin displays antitumor efficacy in a synergistic mouse model of Lewis lung carcinoma. Obtustatin blocks human melanoma growth in nude mice.
| Molecular Weight | 4393.07 |
| Formula | C184H284N52O57S8 |
| Solubility (25°C) | Water ~1 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related Integrin Products |
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| Volociximab
Volociximab (M200) is a chimeric human/murine IgG4 antibody IIA1 targeting integrin α5β1 (EC50=0.2 nM). Volociximab has antiangiogenic and antitumor activities and inhibits the proliferation of human umbilical vein vascular endothelial cells (HUVECs). |
| GSK 3008348 hydrochloride
GSK 3008348 hydrochloride is a small molecule integrin αvβ6 antagonist. |
| HSDVHK-NH2
HSDVHK-NH2 is an antagonist of the integrin αvβ3-vitronectin interaction, with an IC50 of 1.74 pg/mL (2.414 pM). |
| LDV
LDV, a tripeptide, is a non-fluorescent analog of LDV-FITC. |
| Cyclo(RADfK)
Cyclo(RADfK) is a selective α(v)β(3) integrin ligand that has been extensively used for research, therapy, and diagnosis of neoangiogenesis. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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