Free shipping on all orders over $ 500

Nystatin

Cat. No. M3290

All AbMole products are for research use only, cannot be used for human consumption.

Nystatin Structure
Synonym:

Fungicidin; Mycostatin

Size Price Availability Quantity
100mg USD 25  USD25 In stock
500mg USD 50  USD50 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Nystatin (Fungicidin) is a polyene antifungal antibiotic to which many molds and yeasts are sensitive, including Candida spp. Nystatin increases the permeability of plasma membranes to small monovalent ions, including chloridion. Nystatin increases apical chloridion permeability to the point where transepithelial chloridion transport is limited by transport across the basolateral membrane of tracheal epithelial cells, which reflects primarily the activity of the cotransporter. Nystatin (400 units/mL) increases the basal level of transepithelial 36Cl flux approximately 1.5-fold and eliminates UTP stimulation of this flux.

Nystatin combined with endostatin selectively enhances endostatin uptake and biodistribution in tumor blood vessels and tumor tissues but not in normal tissues of tumor-bearing mice, ultimately resulting in elevated antiangiogenic and antitumor efficacies of endostatin in vivo.

Product Citations
Chemical Information
Molecular Weight 926.09
Formula C47H75NO17
CAS Number 1400-61-9
Form Solid
Solubility (25°C) DMSO ≥ 30 mg/mL
Storage -20°C, protect from light, dry, sealed
References

[1] Xin Lyu, et al. Efficacy of nystatin for the treatment of oral candidiasis: a systematic review and meta-analysis

[2] No authors listed. Nurs Times. Nystatin

[3] No authors listed. Nurs Times. Nystatin

[4] S Arikan, et al. Nystatin LF (Aronex/Abbott)

[5] V H Witten, et al. Nystatin

Related Antibiotic Products
Puromycin-d3

Puromycin-d3 is the deuterium labeled Puromycin. Puromycin dihydrochloride is the dihydrochloride salt of puromycin. Puromycin is an aminoglycoside antibiotic that inhibits protein synthesis.

BSH-IN-1

BSH-IN-1 is a potent and covalent inhibitor of gut bacterial recombinant bile salt hydrolases (BSHs) with IC50s of 108 nM and 427 nM for B. longum BSH (Gram positive) and B. theta BSH (Gram negative), respectively.

AAA-10

AAA-10 is an orally active gut bacterial bile salt hydrolases (BSH) inhibitor, with IC50s of 10 nM, 80 nM against B. theta rBSH and B. longum rBSH respectively.

Gut restricted-7

Gut restricted-7 (GR-7) is a potent, covalent and orally active pan-bile salt hydrolase (BSH) inhibitor. Gut restricted-7 has a tissue-selective and is restricted to the gut. Gut restricted-7 decreases gut bacterial BSHs and decreases deconjugated bile acid levels in feces of mice.

N-Hydroxypipecolic acid

N-Hydroxypipecolic acid (1-Hydroxy-2-piperidinecarboxylic acid), a plant metabolite and a systemic acquired resistance (SAR) regulator, orchestrates SAR establishment in concert with the immune signal salicylic acid. N-Hydroxypipecolic acid accumulates systemically in the plant foliage in response to pathogen attack. N-Hydroxypipecolic acid induces SAR to bacterial and oomycete infection.

  Catalog
Abmole Inhibitor Catalog




Keywords: Nystatin, Fungicidin; Mycostatin supplier, Antibiotic, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.