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NVS PAK1 1 is a potent and selective PAK1 inhibitor (IC50 = 5 nM). Selective for PAK1 over PAK2 and a panel of 442 kinases. Inhibits autophosphorylation of PAK1 in KRAS-mutated pancreatic cancer cell lines.
| Molecular Weight | 479.93 |
| Formula | C23H25ClF3N5O |
| CAS Number | 1783816-74-9 |
| Solubility (25°C) | 1eq. HCl 47.99 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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