All AbMole products are for research use only, cannot be used for human consumption.
NSI-189 has been shown to stimulate neurogenesis of human hippocampus-derived neural stem cells in vitro and in vivo.When in vitro，The hippocampus is responsible for the consolidation of information from short-term memory to long-term memory, along with spatial navigation.In vivo，NSI-189 increases the hippocampal volume of healthy adult mice by 20%.
 |
Source | Radiat Res (2018). Figure 6. NSI-189 |
| Method | i.e. | |
| Cell Lines | Rat | |
| Concentrations | 30 mg/kg | |
| Incubation Time | five weeks | |
| Results | Importantly, this radiation-induced deficit was ameliorated significantly by NSI-189 treatment, resulting in an increase (55%) of dual stained granule cell neurons compared to the irradiated cohort |
| Molecular Weight | 366.5 |
| Formula | C22H30N4O |
| CAS Number | 1270138-40-3 |
| Solubility (25°C) | DMSO 60 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related Products |
|---|
| Sulfo-NHS-Biotin
Sulfo-NHS-Biotin stongly label single SDS-2ME soluble cuticular protein. |
| GAPDH-IN-1
GAPDH-IN-1 (GAPDH Inhibitor Compound F8) is a covalent inhibitor of GAPDH (IC50 = 39.31 µM). It viability of, and glucose metabolism in, HEK293 cells in a concentration-dependent manner. |
| O-acetylcamptothecin
O-acetylcamptothecin is a derivative of camptothecin, a naturally occurring alkaloid extracted from the bark of the Chinese tree Camptotheca acuminata. Camptothecin and its derivatives are primarily known for their potent anticancer properties, particularly through their action as inhibitors of topoisomerase I, an enzyme critical for DNA replication and transcription. |
| 10-hydroxystearic acid
10-hydroxystearic acid is a hydroxy fatty acid. |
| SB-T-1214
SB-T-1214 is a new-generation taxoid. SB-T-1214 possesses significant activity against colon cancer spheroids induced by and enriched with drug resistant tumorigenic CD133high/CD44high cells and efficiently inhibited expression of the majority of stem cell-related genes. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.
