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NSC668394 is a potent ezrin (Thr567) phosphorylation inhibitor, with a Kd of 12.59 μM. NSC668394 inhibit ezrin T567 phosphorylation caused by PKCΙ primarily via their binding to ezrin. NSC668394 can be used to prevent tumor metastasis.
| Molecular Weight | 452.1 |
| CAS Number | 382605-72-3 |
| Solubility (25°C) | DMSO 3 mg/mL (ultrasonic and warming and heat to 60°C) |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[5] Haydar elik, et al. Ezrin Inhibition Up-regulates Stress Response Gene Expression
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