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NSC194598

Cat. No. M43522

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NSC194598 Structure
Size Price Availability
5mg USD 750  USD750 1-2 Weeks
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Quality Control & Documentation
Biological Activity

NSC194598 is a p53 DNA-binding inhibitor with IC50 value of 180 nM and 2-40 μM for in vitro and in vivo, respectively.

Chemical Information
Molecular Weight 317.38
Formula C20H19N3O
CAS Number 5358-76-9
Solubility (25°C) DMSO 6 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Qingliang Li et al. Oncogene. Inhibition of p53 DNA binding by a small molecule protects mice from radiation toxicity

[2] Y-J Shin et al. Oncogene. Involvement of G-quadruplex structures in regulation of human RET gene expression by small molecules in human medullary thyroid carcinoma TT cells

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  Catalog
Abmole Inhibitor Catalog




Keywords: NSC194598 supplier, RET, inhibitors, activators

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