Free shipping on all orders over $ 500

NPT200-11

Cat. No. M42721

All AbMole products are for research use only, cannot be used for human consumption.

NPT200-11 Structure

Price and Availability

For this product's availability, delivery time and price, please email [email protected] directly or click the "Inquiry Now" button below.


Quality Control & Documentation
Biological Activity

NPT200-11 is a brain penetrating inhibitor of accumulation of alpha-synuclein (ASYN) misfolding and aggregation.

Chemical Information
Molecular Weight 493.64
Formula C28H39N5O3
CAS Number 2227057-23-8
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Dorothy Das et al. J Biomol Struct Dyn. Computational investigation on the effect of the peptidomimetic inhibitors (NPT100-18A and NPT200-11) on the α-synuclein and lipid membrane interactions

[2] Linda A Hershey et al. Drugs Aging. Pharmacological Management of Dementia with Lewy Bodies

[3] Diana L Price et al. Sci Rep. The small molecule alpha-synuclein misfolding inhibitor, NPT200-11, produces multiple benefits in an animal model of Parkinson's disease

Related Products
D-Allulose

D-Allulose (D-Psicose) is an ultralow-energy monosaccharide sugar. It is a C-3 epimer of D-fructose, and is present in small quantities in agricultural products and commercially-prepared carbohydrate complexes.

N,N-Dimethyltrifluoromethanesulfonamide

N,N-Dimethyltrifluoromethanesulfonamide (DMTMSA) is a trifluoromethanesulfonamide solvent.

Lucicebtide

Lucicebtide is a peptide antagonist of the transcription factor C/EBPβ, a key activator of the transcriptional program in immunosuppressive macrophages. Lucicebtide shows highly potent inhibition against C/EBPB-ATF5 association with IC50 of 24.6 nM in a competitive ELISA assay.

Eloralintide

Eloralintide (LY 3841136) is an AMYR agonist.

Gadoteric acid

Gadoteric acid is a macrocyclic, paramagnetic, gadolinium-based contrast agent that can be used for magnetic resonance imaging (MRI) of the brain, spine, and related tissues. Gadoteric acid is able to detect and visualize areas of blood-brain barrier disruption and abnormal vascular distribution.

  Catalog
Abmole Inhibitor Catalog




Keywords: NPT200-11 supplier, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.