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NPC26 induces mitochondrial fragmentation and cell death in RAS expressing cells, similar to erastin. The effects of NPC26 are independent of ROS scavengers, which can block cell death induced by erastin.
| Molecular Weight | 437.53 |
| Formula | C19H23N3O5S2 |
| CAS Number | 864860-32-2 |
| Solubility (25°C) | DMSO: 2 mg/mL (warmed) |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Zhen Zhao, et al. NPC-26 kills human colorectal cancer cells via activating AMPK signaling
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