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Nomegestrol acetate (NOMAc) is a potent, highly selective progestogen, a full agonist at the progesterone receptor, with no or minimal binding to other steroid receptors. It shows potent antigonadotropic activity mediated at the hypothalamic and pituitary level with strong antiestrogenic effects and a partial antiandrogenic effect. NOMAc is used in various formulations as a contraceptive.
| Molecular Weight | 370.48 |
| Formula | C23H30O4 |
| CAS Number | 58652-20-3 |
| Solubility (25°C) | DMSO: ≥7 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[2] Xiangyan Ruan, et al. The pharmacology of nomegestrol acetate
[3] Stefano Lello. Nomegestrol acetate: pharmacology, safety profile and therapeutic efficacy
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