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NF340 

Cat. No. M29114

All AbMole products are for research use only, cannot be used for human consumption.

NF340  Structure

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Quality Control & Documentation
Biological Activity

NF340 is a potent and selective P2Y11 receptor antagonist. NF340 inhibits the activity of P2Y11R by completely combining with ATP-binding amino acid residues. NF340 ameliorates inflammation in human fibroblast-like synoviocytes and can be used for rheumatoid arthritis research.

Chemical Information
Molecular Weight 986.84
Formula C37H26N4Na4O15S4
CAS Number 202982-98-7
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Georg Gruenbacher, et al. Br J Pharmacol. The human G protein-coupled ATP receptor P2Y11 is a target for anti-inflammatory strategies

[2] Feng Gao, et al. IUBMB Life. P2Y11 receptor antagonist NF340 ameliorates inflammation in human fibroblast-like synoviocytes: An implication in rheumatoid arthritis

[3] Tingting Zhang, et al. ChemistryOpen. Sulfonated Compounds Bind with Prostatic Acid Phosphatase (PAP248-286) to Inhibit the Formation of Amyloid Fibrils

[4] Charles Kennedy. Adv Exp Med Biol. P2Y11 Receptors: Properties, Distribution and Functions

[5] Karin Dreisig, et al. Purinergic Signal. A critical look at the function of the P2Y11 receptor

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  Catalog
Abmole Inhibitor Catalog




Keywords: NF340  supplier, P2 Receptor, inhibitors, activators

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