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Neriifolin

Cat. No. M11049

All AbMole products are for research use only, cannot be used for human consumption.

Neriifolin Structure
Synonym:

17β-Neriifolin

Size Price Availability Quantity
1mg USD 240  USD240 In stock
5mg USD 425  USD425 In stock
10mg USD 680  USD680 In stock
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Quality Control & Documentation
Biological Activity

Neriifolin, a cardiac glycoside that penetrates the central nervous system, is a typeNa, K-ATPase++ of inhibitors. Neriifolin targets beclin 1, inhibits the formation of LC3-associated phagosomes, and improves the development of experimental autoimmune encephalomyelitis (EAE).

Chemical Information
Molecular Weight 534.68
Formula C30H46O8
CAS Number 466-07-9
Solubility (25°C) DMSO ≥ 60 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Nurhanan M Yunos, et al. Curr Pharm Biotechnol. The In Vitro Anti-Cancer Activities of 17βH-Neriifolin Isolated from Cerbera odollam and its Binding Activity on Na+, K+-ATPase

[2] Ali A Alzabib, et al. Pest Manag Sci. Molluscicidal activity of cardiac glycosides isolated from Adenium obesum

[3] Ravi Prakash Yadav, et al. Food Chem. Neriifolin S, a dimeric serine protease from Euphorbia neriifolia Linn.: Purification and biochemical characterisation

[4] Siti-Syarifah Mohd Mutalip, et al. Anticancer Res. Mechanisms of action of 17βH-neriifolin on its anticancer effect in SKOV-3 ovarian cancer cell line

[5] Qian Zhao, et al. Fitoterapia. Neriifolin from seeds of Cerbera manghas L. induces cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells

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Keywords: Neriifolin, 17β-Neriifolin supplier, inhibitors, activators

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