All AbMole products are for research use only, cannot be used for human consumption.
Nepicastat is a dopamine beta-hydroxylase inhibitor with IC50 of 8.5 ±0.8 and 9.0 ±0.8 nM for bovine and human, respectively. Dopamine beta-hydroxylase is an enzyme that catalyzes the conversion of dopamine to norepinephrine. It has been studied as a possible treatment for congestive heart failure, and appears to be well tolerated as such.
| Cell Experiment | |
|---|---|
| Cell lines | |
| Preparation method | |
| Concentrations | |
| Incubation time | |
| Animal Experiment | |
|---|---|
| Animal models | Spontaneously hypertensive rats (SHRs). |
| Formulation | Nepicastat hydrochloride is dissolved in distilled water. |
| Dosages | ≤100 mg/kg |
| Administration | Administered via p.o. |
| Molecular Weight | 295.35 |
| Formula | C14H15F2N3S |
| CAS Number | 173997-05-2 |
| Solubility (25°C) | DMSO |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related Products |
|---|
| N-(tert-Butoxycarbonyl)-L-glutamine
N-(tert-Butoxycarbonyl)-L-glutamine is an important amino acid derivative, with the general chemical properties of amino acids, can be used as organic synthesis and biochemical intermediates, mostly used in the synthesis of peptide biomolecules and bioactive molecules. BOC-L-glutamine and its derivatives can also be used in the study of biological activities. |
| Boc-D-Ala-OMe
Boc-D-Ala-OMe is a biochemical material that can be used in scientific research. Boc-D-Ala-OMe is also an amino acid derivative. |
| 2-Bromo-4-chlorophenylacetic acid
2-Bromo-4-chlorophenylacetic acid is a biochemical reagent. |
| CPN-351 TFA
CPN-351 TFA is a selective pentapeptide antagonist of human NMUR1 with a pA2 of 7.35. CPN-351 TFA can be used for the research of inflammation. |
| 5-Phenyluracil
5-Phenyluracil is a pyrimidine derivative, a class of heterocyclic aromatic organic compounds crucial in biochemistry. It serves as a synthetic nucleoside analogue, meaning it mimics the structure of naturally occurring nucleosides like uridine. This structural similarity allows it to participate in biochemical reactions, often interfering with normal cellular processes, making it a valuable tool in studying nucleic acid metabolism and developing antiviral and anticancer agents. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.
