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Nefopam

Cat. No. M28264

All AbMole products are for research use only, cannot be used for human consumption.

Nefopam Structure
Synonym:

Fenazoxine

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Quality Control & Documentation
Biological Activity

Nefopam (Fenazoxine) is an orally active, non-opioid and non-steroidal centrally acting analgesic agent. Nefopam blocks voltage-sensitive sodium channels (IC50=27 µM) and modulates glutamatergic transmission in rodents. Nefopam can be used in studies of neuropathic pain, anticonvulsant, as well as the prevention of postoperative shivering and hiccups.

Chemical Information
Molecular Weight 253.34
Formula C17H19NO
CAS Number 13669-70-0
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Thomas Schulz, et al. Pan Afr Med J. Nefopam prescribing preferences in French hospitals: results of a survey

[2] Bruno Revol, et al. Therapie. [Thirty years of nefopam abuse in France]

[3] No authors listed. Nefopam

[4] Philippe Girard, et al. Clin Exp Pharmacol Physiol. Nefopam analgesia and its role in multimodal analgesia: A review of preclinical and clinical studies

[5] M S Evans, et al. Br J Anaesth. Nefopam for the prevention of postoperative pain: quantitative systematic review

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Keywords: Nefopam, Fenazoxine supplier, inhibitors, activators

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