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NE-CARBOXYMETHYL-L-LYSINE

Cat. No. M13377
NE-CARBOXYMETHYL-L-LYSINE Structure
Synonym:

N6-(Carboxymethyl)lysine

Size Price Availability Quantity
1mg USD 250  USD250 In stock
5mg USD 750  USD750 In stock
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Quality Control & Documentation
Biological Activity

NE-CARBOXYMETHYL-L-LYSINE

Chemical Information
Molecular Weight 204.22
Formula C8H16N2O4
CAS Number 5746-04-3
Storage -20°C
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Wei Zhang, et al. Food Chem. Corrigendum to "Methylglyoxal-hydroimidazolones (MG-Hs) instead of Nɛ-(carboxymethyl)-l-lysine (CML) is the major advanced glycation end-product during drying process in black tea" [Food Chem. 333 (2020) 127499]

[2] Wei Zhang, et al. Food Chem. Methylglyoxal-hydroimidazolones (MG-Hs) instead of Nɛ-(carboxymethyl)-l-lysine (CML) is the major advanced glycation end-product during drying process in black tea

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Keywords: NE-CARBOXYMETHYL-L-LYSINE, N6-(Carboxymethyl)lysine supplier, inhibitors, activators


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