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NE-100 (hydrochloride) is a potent and selective sigma-1 receptor antagonist with an IC50 of 4.16 nM. NE-100 (hydrochloride) exerts antipsychotic activity in vivo. NE-100 (hydrochloride) also suppresses ER stress-induced hippocampal cell death.
| Molecular Weight | 391.97 |
| Formula | C23H34ClNO2 |
| CAS Number | 149409-57-4 |
| Form | Solid |
| Solubility (25°C) | DMSO 250 mg/mL (ultrasonic) Water ≥ 100 mg/mL |
| Storage | -20°C, dry, sealed |
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