Free shipping on all orders over $ 500

NCX 4016

Cat. No. M8606

All AbMole products are for research use only, cannot be used for human consumption.

NCX 4016 Structure

Price and Availability

For this product's availability, delivery time and price, please email [email protected] directly or click the "Inquiry Now" button below.


Quality Control & Documentation
Biological Activity

NCX 4016 (nitroaspirin) is nitroderivative of aspirin that combines cyclooxygenase inhibitor with an NO donor. NCX 4016 improves postischemic ventricular dysfunction and to reduce myocardial infarct size in rabbit.

Chemical Information
Molecular Weight 331.28
Formula C16H13NO7
CAS Number 175033-36-0
Solubility (25°C) DMSO: 25 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Narasimham L Parinandi, et al. Nitroaspirin (NCX-4016), an NO donor, is antiangiogenic through induction of loss of redox-dependent viability and cytoskeletal reorganization in endothelial cells

[2] Paolo Gresele, et al. Pharmacologic profile and therapeutic potential of NCX 4016, a nitric oxide-releasing aspirin, for cardiovascular disorders

[3] Nirmal S Mann. No-Aspirin (NCX 4016)

[4] Mario Di Napoli, et al. NCX-4016 NicOx

[5] Stefano Fiorucci, et al. NCX-4016 (NO-aspirin) inhibits lipopolysaccharide-induced tissue factor expression in vivo: role of nitric oxide

Related Products
Myoglobin (from equine skeletal muscle)

Myoglobin is a small molecular pigment protein formed by binding globin to Heme, which can be reversibly bound to oxygen to form MbO2, MbO2 is called oxymyoglobin, and Mb is called deoxymyoglobin. Myoglobin has the role of transporting and storing oxygen in muscle cells.

Hemoglobin (from bovine blood)

Hemoglobin is a iron-containing protein in red blood cells with oxygen binding properties. Hemoglobin is an inducer of HO-1. Hemoglobin consits of heme, which binds to oxygen. Hemoglobin also transports other gases, such as carbon dioxide, nitric oxide, hydrogen sulfide and sulfide.

Diethylenetriaminepentaacetic dianhydride

Diethylenetriaminepentaacetic dianhydride (DTPA anhydride) is a bifunctional chelator whose anhydride can react with amino groups in proteins (such as lysine residues) to form stable amide bonds. Diethylenetriaminepentaacetic dianhydride (DTPA anhydride) can also bind to radionuclides to synthesize radionuclide-labeled drug conjugates (RDCs).

3-Phenylthiophene

3-Phenylthiophene is a biochemical material that can be used in scientific research. 3-Phenylthiophene is a conducting polymer precursor.

DSPE-PEG-FA

DSPE-PEG2K-FA is a PEG derivative containing folic acid. DSPE-PEG2K-FA has a targeting effect and can bind to folic acid receptors in cancer cells. DSPE-PEG2K-FA forms micelles/lipid bilayers and can be used in research on targeted drug delivery systems.

  Catalog
Abmole Inhibitor Catalog




Keywords: NCX 4016 supplier, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.