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NAD+

Cat. No. M9086

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NAD+ Structure
Synonym:

β-DPN; β-NAD; Coenzyme 1; Nadide;β-Nicotinamide Adenine Dinucleotide

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500mg USD 40  USD40 In stock
1g USD 50  USD50 In stock
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Biological Activity

NAD+, nicotinamide adenine dinucleotide, is a coenzyme that transfers hydrogen ions and is formed by the coupling of ribosylnicotinamide 5'-diphosphate to adenosine 5'-phosphate via pyrophosphate bonding. NAD+ is the oxidized form of NADH. NAD+ is a coenzyme that is formed by the coupling of ribosylnicotinamide 5'-diphosphate to adenosine 5 '-phosphate coupled by pyrophosphate bonding.

Product Citations
Customer Product Validations & Biological Datas
Source Nat Commun (2021 Mar). Figure 1. NAD+ (Abmole Bioscience)
Method Protein expression and enzyme activities
Cell Lines Plasmids p90, p91, p92, and p98
Concentrations 2.0 mM
Incubation Time 1 min
Results 3HP production via metabolic engineering started from 1,3-propanediol could avoid the paradox between glycerol dehydratase and aldehyde dehydrogenase activities, which generate from the imbalance of vita min B12 synthesis and NAD+ regeneration.
Chemical Information
Molecular Weight 663.43
Formula C21H27N7O14P2
CAS Number 53-84-9
Solubility (25°C) Water 50 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Andrew R Mendelsohn, et al. Interacting NAD + and Cell Senescence Pathways Complicate Antiaging Therapies

[2] Luis Rajman, et al. Therapeutic Potential of NAD-Boosting Molecules: The In Vivo Evidence

[3] Daniel S Matasic, et al. Emerging potential benefits of modulating NAD + metabolism in cardiovascular disease

[4] Kristin A Anderson, et al. Metabolic control by sirtuins and other enzymes that sense NAD +, NADH, or their ratio

[5] G Sultani, et al. NAD + : A key metabolic regulator with great therapeutic potential

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Keywords: NAD+, β-DPN; β-NAD; Coenzyme 1; Nadide;β-Nicotinamide Adenine Dinucleotide supplier, Enzymes & Coenzymes, inhibitors, activators

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